Burden and Risk Factors for Coronavirus Infections in Infants in Rural Nepal.

ABSTRACT:

Background

Knowledge of risk factors for symptomatic human coronavirus (HCoV) infections in children in community settings is limited. We estimated the disease burden and impact of birth-related, maternal, household, and seasonal factors on HCoV infections among children from birth to 6 months old in rural Nepal.

Methods

Prospective, active, weekly surveillance for acute respiratory infections (ARIs) was conducted in infants over a period of 3 years during 2 consecutive, population-based randomized trials of maternal influenza immunization. Midnasal swabs were collected for acute respiratory symptoms and tested for HCoV and other viruses by reverse-transcription polymerase chain reaction. Association between HCoV incidence and potential risk factors was modeled using Poisson

SUBMITTER: Uddin SMI 

PROVIDER: S-EPMC6206108 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature