A simple clinical model predicts incident hepatic steatosis in a community-based cohort: The Framingham Heart Study.

ABSTRACT:

Background and aims

The factors associated with incident hepatic steatosis are not definitively known. We sought to determine factors associated with incident hepatic steatosis, as measured on computed tomography, in the community.

Methods

We studied Framingham Heart Study participants without heavy alcohol use or baseline hepatic steatosis who underwent computed tomography scans between 2002-2005 (baseline) and 2008-2011 (follow-up). We performed a stepwise logistic regression procedure to determine the predictors associated with incident hepatic steatosis.

Results

We included 685 participants (mean age: 45.0 ± 6.2 years, 46.8% women). The incidence of hepatic steatosis in our sample was 17.1% over a mean 6.3 years of follow-up. Participants who developed hepatic ste

SUBMITTER: Long MT 

PROVIDER: S-EPMC6206437 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature