Hyperchloremia and postoperative acute kidney injury: a retrospective analysis of data from the surgical intensive care unit.

ABSTRACT:

Background

Whether perioperative hyperchloremia can induce postoperative acute kidney injury (AKI) is controversial. We investigated the association between perioperative hyperchloremia and postoperative AKI in patients admitted to the intensive care unit (ICU) after surgery.

Methods

We performed a retrospective observational study of patients admitted to the surgical ICU at a single tertiary care hospital between January 2011 and June 2016. Our primary objective was to determine whether hyperchloremia or an increase in serum chloride levels was associated with postoperative AKI. Perioperative hyperchloremia was defined as serum chloride levels ≥ 110 mmol·L^- 1 during postoperative days (PODs) 0-3. The increase in serum chloride levels was defined as the difference

SUBMITTER: Oh TK 

PROVIDER: S-EPMC6206638 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature