SwissMTB: establishing comprehensive molecular cancer diagnostics in Swiss clinics.

ABSTRACT:

Background

Molecular precision oncology is an emerging practice to improve cancer therapy by decreasing the risk of choosing treatments that lack efficacy or cause adverse events. However, the challenges of integrating molecular profiling into routine clinical care are manifold. From a computational perspective these include the importance of a short analysis turnaround time, the interpretation of complex drug-gene and gene-gene interactions, and the necessity of standardized high-quality workflows. In addition, difficulties faced when integrating molecular diagnostics into clinical practice are ethical concerns, legal requirements, and limited availability of treatment options beyond standard of care as well as the overall lack of awareness of their existence.

Methods

To th

SUBMITTER: Singer F 

PROVIDER: S-EPMC6206832 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature