Acute cholecystitis - a cohort study in a real-world clinical setting (REWO study, NCT02796443).

ABSTRACT:

Background

For decades, the optimal timing of surgery for acute cholecystitis has been controversial. Recent meta-analyses and population-based studies favor early surgery. One recent large randomized trial has demonstrated that a delayed approach increases morbidity and cost compared to early surgery within 24 hours of hospital admission. Since cases of severe cholecystitis were excluded from this trial, we argue that these results do not reflect real-world clinical situations. From our point of view, these results were in contrast to the clinical experience with our patients; so, we decided to analyze critically all our patients with the null hypothesis that the patients treated with a delayed cholecystectomy after an acute cholecystitis have a similar or even better outcome than

SUBMITTER: Blythe J 

PROVIDER: S-EPMC6207389 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature