Maternal-fetal transmission and adverse perinatal outcomes in pregnant women infected with Zika virus: prospective cohort study in French Guiana.

ABSTRACT:

Objectives

To estimate the rates of maternal-fetal transmission of Zika virus, adverse fetal/neonatal outcomes, and subsequent rates of asymptomatic/symptomatic congenital Zika virus infections up to the first week of life.

Design

Cohort study with prospective data collection and subsequent review of fetal/neonatal outcomes.

Settings

Referral centre for prenatal diagnosis of the French Guiana Western Hospital.

Participants

Pregnant women at any stage of pregnancy with a laboratory confirmed symptomatic or asymptomatic Zika virus infection during the epidemic period in western French Guiana. The cohort enrolled 300 participants and prospectively followed their 305 fetuses/newborns.

Main outcome measures

Rate of maternal-fetal transmission of Zika virus (a

SUBMITTER: Pomar L 

PROVIDER: S-EPMC6207920 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature