Impact of primary breast cancer therapy on energetic capacity and body composition.

ABSTRACT:

Purpose

This observational study was designed to measure baseline energy parameters and body composition in early-stage breast cancer patients, and to follow changes during and after various modalities of treatment. This will provide information to aid in the development of individualized physical activity intervention strategies.

Methods

Patients with newly diagnosed stage 0-III breast cancer were enrolled into three cohorts: A (local therapy alone), B (endocrine therapy), or C (chemotherapy with or without endocrine therapy). At baseline, 6 months, and 12 months, subjects underwent a stationary bicycle protocol to assess power generation and DEXA to assess body composition.

Results

Eighty-three patients enrolled. Patients had low and variable levels of power generat

SUBMITTER: Ballinger TJ 

PROVIDER: S-EPMC6208924 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature