Frontostriatal pathways gate processing of behaviorally relevant reward dimensions.

ABSTRACT: The value of rewards arises from multiple hedonic and motivational dimensions. Reward-encoding brain regions such as the ventral striatum (VS) are known to process these dimensions. However, the mechanism whereby distinct reward dimensions are selected for neural processing and guiding behavior remains unclear. Here, we used functional imaging to investigate how human individuals make either hedonic (liking) or motivational (wanting) evaluations of everyday items. We found that the two types of evaluations were differently modulated depending on whether participants won or lost these items. Neural activity in the VS encoded both hedonic and motivational dimensions of reward, whereas ventromedial prefrontal activity encoded primarily motivational evaluations and central orbitofrontal activi

SUBMITTER: Weber SC 

PROVIDER: S-EPMC6209378 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature