Changes in temperature alter the potential outcomes of virus host shifts.

ABSTRACT: Host shifts-where a pathogen jumps between different host species-are an important source of emerging infectious disease. With on-going climate change there is an increasing need to understand the effect changes in temperature may have on emerging infectious disease. We investigated whether species' susceptibilities change with temperature and ask if susceptibility is greatest at different temperatures in different species. We infected 45 species of Drosophilidae with an RNA virus and measured how viral load changes with temperature. We found the host phylogeny explained a large proportion of the variation in viral load at each temperature, with strong phylogenetic correlations between viral loads across temperature. The variance in viral load increased with temperature, while the mean vir

SUBMITTER: Roberts KE 

PROVIDER: S-EPMC6209381 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature