Dietary Arginine Supplementation Affects Intestinal Function by Enhancing Antioxidant Capacity of a Nitric Oxide-Independent Pathway in Low-Birth-Weight Piglets.

ABSTRACT:

Background

Low-birth-weight (LBW) neonates are susceptible to intestinal dysfunction. Furthermore, the antioxidant capacity of LBW neonates is significantly lower compared with that of normal-birth-weight (NBW) neonates both at birth and at weaning. In LBW neonates, dietary supplementation with arginine has shown beneficial effects on intestinal function.

Objective

The present study explored the potential mechanisms of arginine-induced protective effects against intestinal dysfunction in LBW piglets.

Methods

Forty 4-d-old LBW piglets [body weight (BW): 1.05 ± 0.04 kg] (Large White × Landrace) were assigned to 4 treatments and artificially fed a whole-milk powder- and whey protein concentrate-based diet (containing 0.65% arginine) either not supplemented with arginine

SUBMITTER: Zheng P 

PROVIDER: S-EPMC6209807 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature