Prevalence of blaKPC and its occurrence with other beta-lactamases in Klebsiella pneumoniae.

ABSTRACT:

Background

Klebsiella pneumoniae (K. pneumoniae) is an important nosocomial pathogen, and the emergence of multidrug resistance in these organisms limits the treatment options for serious infections caused by them. K. pneumoniae carbapenemase (KPC) is one of the clinically significant Class A beta-lactamases.

Aim and objective

This study was aimed to detect the KPC and its coexistence with other beta-lactamases in K. pneumoniae.

Materials and methods

A total of 370 isolates, collected over a period of 1 year, were included in this study. The source of these isolates were urine (n = 170), exudative specimens (n = 132), respiratory secretions such as bronchial wash, endotracheal aspirate, and pleural fluid (n = 38), and b

SUBMITTER: Remya P 

PROVIDER: S-EPMC6210832 | biostudies-literature | 2018 Oct-Dec

REPOSITORIES: biostudies-literature