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Sequence Variation in Multidrug-Resistant Plasmid pLUH01, Isolated from Human Nasopharyngeal Swabs.


ABSTRACT: Three variants of the multidrug-resistant plasmid pLUH01 were assembled by deep sequencing from nasopharyngeal swabs. All have a 21-bp deletion in the RS14515 hypothetical gene. Variants 1 through 3 have 2, 6, and 3 nucleotide substitutions, respectively, compared to the pLUH01 reference genome. We named the new plasmid variants pLUH01/Lancaster/2015/1 to pLUH01/Lancaster/2015/3.

SUBMITTER: Atkinson KV 

PROVIDER: S-EPMC6211343 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature

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Sequence Variation in Multidrug-Resistant Plasmid pLUH01, Isolated from Human Nasopharyngeal Swabs.

Atkinson Kate V KV   Bishop Lisa A LA   Rhodes Glenn G   Salez Nicolas N   McEwan Neil R NR   Hegarty Matthew J MJ   Robey Julie J   Harding Nicola N   Wetherell Simon S   Lauder Robert M RM   Pickup Roger W RW   Wilkinson Mark M   Gatherer Derek D  

Microbiology resource announcements 20180712 1


Three variants of the multidrug-resistant plasmid pLUH01 were assembled by deep sequencing from nasopharyngeal swabs. All have a 21-bp deletion in the RS14515 hypothetical gene. Variants 1 through 3 have 2, 6, and 3 nucleotide substitutions, respectively, compared to the pLUH01 reference genome. We named the new plasmid variants pLUH01/Lancaster/2015/1 to pLUH01/Lancaster/2015/3. ...[more]

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