A Common Variation in the Caveolin 1 Gene Is Associated with High Serum Triglycerides and Metabolic Syndrome in an Admixed Latin American Population.

ABSTRACT:

Background

The caveolin 1 (CAV1) gene has been associated with metabolic traits in animal models and human cohorts. Recently, a prevalent variant in CAV1 has been found to be related to metabolic syndrome in Hispanics living in North America. Since Hispanics represent an admixed population at high risk for cardiovascular diseases, in this study a Latin American population with a similar genetic background was assessed.

Objective

To analyze a genetic association between CAV1 and metabolic traits in an admixed Latin American population.

Methods

A cross-sectional study was carried out with adults from the Colombian Caribbean Coast, selected in urban clusters and work places through a stratified sampling to include diverse ages and socioeconomic groups. Blood pressure and

SUBMITTER: Mora-Garcia G 

PROVIDER: S-EPMC6211369 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature