Deep taxon sampling reveals the evolutionary dynamics of novel gene families in Pristionchus nematodes.

ABSTRACT: The widespread identification of genes without detectable homology in related taxa is a hallmark of genome sequencing projects in animals, together with the abundance of gene duplications. Such genes have been called novel, young, taxon-restricted, or orphans, but little is known about the mechanisms accounting for their origin, age, and mode of evolution. Phylogenomic studies relying on deep and systematic taxon sampling and using the comparative method can provide insight into the evolutionary dynamics acting on novel genes. We used a phylogenomic approach for the nematode model organism Pristionchus pacificus and sequenced six additional Pristionchus and two outgroup species. This resulted in 10 genomes with a ladder-like phylogeny, sequenced in one laboratory using the sa

SUBMITTER: Prabh N 

PROVIDER: S-EPMC6211646 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature