Hormonal biomarkers for the noninvasive diagnosis of endometriosis: A protocol for a network meta-analysis of diagnostic test accuracy.

ABSTRACT:

Background

Endometriosis is a major cause of disability and compromised the quality of life in women and teenage girls. The gold standard for diagnosis of endometriosis is laparoscopy with histology of excised endometriosis lesions. However, women can suffer for 8 to 12 years before obtaining a correct diagnosis. Several biomarkers showed good diagnostic value for endometriosis, but no studies directly or indirectly compare the diagnostic value of different biomarkers. We perform this network meta-analysis (NMA) to assess the diagnostic accuracy of hormonal biomarkers, and to find a most effective hormonal biomarker for the diagnosis of endometriosis.

Methods

A systematic search will be performed using PubMed, EMBASE, Cochrane Library and Chinese Biomedicine Literature to id

SUBMITTER: Shen M 

PROVIDER: S-EPMC6211906 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature