Early severe coronary heart disease and ischemic heart failure in homozygous familial hypercholesterolemia: A case report.

ABSTRACT:

Rationale

Familial hypercholesterolemia (FH) is a common inherited cause of coronary heart disease (CHD) and premature death in an early age. Nevertheless, an ischemic heart failure (IHF) associated with FH seems to be rare, and an early diagnosis and therapy could influence the prognosis.

Patient concerns

In this 13-year-old girl, multiple xanthomas began to develop from the first day of birth. Until June, 2017, she was admitted to our center due to edema, oliguria, and dyspnea during exertion, which was attributed to a recent respiratory infection.

Diagnosis

Homozygous FH (HoFH), CHD, and IHF.

Interventions

The patient has been treated with statin, ezetimibe, aspirin, and traditional heart failure (HF) medications. In addition, the beta-blocker was simultaneo

SUBMITTER: Kuang H 

PROVIDER: S-EPMC6211926 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature