Extent of linkage disequilibrium and effective population size of Korean Yorkshire swine.

ABSTRACT:

Objective

We aimed to characterize linkage disequilibrium (LD) and effective population size (Ne) in a Korean Yorkshire population using genomic data from thousands of individuals.

Methods

We genotyped 2,470 Yorkshire individuals from four major Grand-Grand-Parent farms in Korea using the Illumina PorcineSNP60 version2 BeadChip, which covers >61,565 single nucleotide polymorphisms (SNPs) located across all chromosomes and mitochondria. We estimated the expected LD and inferred current Ne as well as ancestral Ne.

Results

We identified 61,565 SNP from autosomes, mitochondria, and sex chromosomes and characterized the LD of the Yorkshire population, which was relatively high between closely linked markers (>0.55 at 50 kb) and declined with increasing genetic distance. Th

SUBMITTER: Shin D 

PROVIDER: S-EPMC6212734 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature