Association of polymorphisms in Pit-1 gene with growth and feed efficiency in meat-type chickens.

ABSTRACT:

Objective

The pituitary specific transcription factor-1 (Pit-1) gene is responsible for pituitary development and growth hormone expression and is regarded as a pivotal candidate gene for growth and production in chickens. Therefore, the aim of this study was to investigate the association of Pit-1 polymorphisms with growth and feed efficiency traits in yellow meat-type chickens.

Methods

In the present study, five single nucleotide polymorphisms (SNPs) of Pit-1 were selected and genotyped by high-throughput matrix-assisted laser desorption-ionization time-of-flight mass spectrometry in 724 meat-type chickens.

Results

Association analysis showed that rs13687126 of Pit-1 was strongly associated with body weight gain (BWG) and feed intake (FI) (p<0.05), and that rs136871

SUBMITTER: Jin S 

PROVIDER: S-EPMC6212749 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature