Ontology highlight
ABSTRACT:
SUBMITTER: Rioux G
PROVIDER: S-EPMC6213003 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Rioux Geneviève G Pouliot-Bérubé Claudia C Simard Mélissa M Benhassine Manel M Soucy Jacques J Guérin Sylvain L SL Pouliot Roxane R
International journal of molecular sciences 20180926 10
Psoriasis is a chronic inflammatory skin disease for which no cure has emerged. Its complex etiology requires the development of an in vitro model representative of the pathology. In this study, we exploited gene profiling analyses on microarray in order to characterize and further optimize the production of a human psoriatic skin model representative of this in vivo skin disease. Various skin substitutes were produced by tissue-engineering using biopsies from normal, healthy donors, or from les ...[more]