High Fat/High Glucose Diet Induces Metabolic Syndrome in an Experimental Rat Model.

ABSTRACT: Metabolic syndrome (MetS) is defined as a constellation of many metabolic disorders such as hypertension, impaired glucose tolerance, dyslipidemia and obesity, being this last disorder a key factor in the etiology of the syndrome. The widespread of MetS in actual society, mainly in developed countries, is becoming an important health problem and is increasing the need to develop new treatments against this pathology is increasing fast. The main objective of the present study was to evaluate the MetS-associated alterations developed in a new glucose diet-induced-obesity (DIO) rodent model. These alterations were also compared to those alterations developed in a fructose-DIO rodent model. Wistar rats were divided into four groups: Control (C), High-fat (HF), High-fat/high-fructose (HFF) and

SUBMITTER: Moreno-Fernandez S 

PROVIDER: S-EPMC6213024 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature