CPEB2 Is Necessary for Proper Porcine Meiotic Maturation and Embryonic Development.

ABSTRACT: Oocyte meiotic maturation and embryogenesis are some of the most important physiological processes that occur in organisms, playing crucial roles in the preservation of life in all species. The post-transcriptional regulation of maternal messenger ribonucleic acids (mRNAs) and the post-translational regulation of proteins are critical in the control of oocyte maturation and early embryogenesis. Translational control affects the basic mechanism of protein synthesis, thus, knowledge of the key components included in this machinery is required in order to understand its regulation. Cytoplasmic polyadenylation element binding proteins (CPEBs) bind to the 3'-end of mRNAs to regulate their localization and translation and are necessary for proper development. In this study we examined the expres

SUBMITTER: Prochazkova B 

PROVIDER: S-EPMC6214008 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature