Single dose partial breast irradiation using an MRI linear accelerator in the supine and prone treatment position.

ABSTRACT:

Background

In selected patients with early-stage and low-risk breast cancer, an MRI-linac based treatment might enable a radiosurgical, non-invasive alternative for current standard breast conserving therapy.

Aim

To investigate whether single dose accelerated partial breast (APBI) to the intact tumor in both the prone and supine radiotherapy positions on the MRI-linac is dosimetrically feasible with respect to predefined coverage and organs at risk (OAR) constraints.

Material & methods

For 20 patients with cTis or low-risk cT1N0M0 non-lobular breast carcinoma, previously treated with single dose preoperative APBI in the supine (n = 10) or prone (n = 10) position, additional intensity modulated radiotherapy plans with 7 coplanar beams in the presence of a 1.5T magnetic

SUBMITTER: Charaghvandi KR 

PROVIDER: S-EPMC6215022 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature