Unique divergence of the breast cancer 2 (BRCA2) gene in Neanderthals.

ABSTRACT: Unique divergence of the BRCA2, a tumor suppressor gene, in Neanderthals relative to other primates, including modern humans, is highlighted. This divergence with potentially pathogenic consequences raises a question about cancer susceptibility in the archaic species that was replaced by modern humans about 40,000 years ago.

SUBMITTER: Michalak P 

PROVIDER: S-EPMC6215347 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature