Critical Language Areas Show Increased Functional Connectivity in Human Cortex.

ABSTRACT: Electrocortical stimulation (ECS) mapping is routinely used to identify critical language sites before resective neurosurgery. The precise locations of these sites are highly variable across patients, occurring in the frontal, temporal, and parietal lobes-it is this variability that necessitates individual patient mapping. But why these particular anatomical sites are so privileged in each patient is unknown. We hypothesized that critical language sites have greater functional connectivity with nearby cortex than sites without critical functions, since they serve as central nodes within the language network. Functional connectivity across language, motor, and cleared sites was measured in 15 patients undergoing electrocortiographic (ECoG) mapping for epilepsy surgery. Critical language sit

SUBMITTER: Rolston JD 

PROVIDER: S-EPMC6215463 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature