Neoantigens in Ovarian Cancer: Embarrassment of Riches or Needles in a Haystack?

ABSTRACT: Comprehensive genomic and transcriptomic analysis demonstrate that tumor-infiltrating T lymphocytes that react to mutated neoepitopes could be identified in recurrent ovarian cancer. Two of these T-cell populations reacted against TP53 hotspot missense mutations that are present in a wide variety of malignancies. Clin Cancer Res; 24(22); 5493-5. ©2018 AACR See related article by Deniger et al., p. 5562.

SUBMITTER: McNeish IA 

PROVIDER: S-EPMC6215482 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature