Association of food allergy and decreased lung function in children and young adults with asthma.

ABSTRACT:

Background

Food allergy (FA) appears early in the atopic march, a progression that may lead to the development of asthma. The association between FA and pulmonary function in children with and without asthma remains unknown.

Objective

To investigate the association between FA and lung function in children with and without asthma.

Methods

We enrolled 1,068 children as a part of a family-based FA cohort. We then categorized children as having FA by physician diagnosis, evidence of specific IgE, and typical symptoms within 2 hours of food ingestion. We categorized asthma by physician diagnosis. We used American Thoracic Society criteria for spirometry measurements. We assessed the effects of asthma classification and FA number on lung function using mixed-effect models.<

SUBMITTER: Sherenian MG 

PROVIDER: S-EPMC6215513 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature