Sexual function and combined oral contraceptives: a randomised, placebo-controlled trial.

ABSTRACT:

Objective

The effect of combined oral contraceptives (COCs) on female sexuality has long been a matter of discussion, but placebo-controlled studies are lacking. Thus, the aim of the present study was to investigate if an oestradiol-containing COC influences sexual function.

Design

Investigator-initiated, randomised, double-blinded, placebo-controlled clinical trial where 202 healthy women were randomised to a combined oral contraceptive (1.5 mg oestradiol and 2.5 mg nomegestrol acetate) or placebo for three treatment cycles.

Methods

Sexual function at baseline and during the last week of the final treatment cycle was evaluated by the McCoy Female Sexuality Questionnaire. Serum and hair testosterone levels were assessed at the same time points.

Results

Compared

SUBMITTER: Lundin C 

PROVIDER: S-EPMC6215801 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature