Glycemic extremes are related to cognitive dysfunction in children with type 1 diabetes: A meta-analysis.

ABSTRACT:

Aims/introduction

To examine the magnitude and pattern of cognitive dysfunction in children with type 1 diabetes, and the possible effects associated with other disease variables, such as early onset diabetes, severe hypoglycemia and hyperglycemia.

Materials and methods

We carried out a meta-analysis using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. We searched MedLine, Embase and PsycINFO to identify studies on cognitive function in children with type 1 diabetes that were published up until 30 September 2016. Effect sizes understood as the standardized mean differences between groups with diabetes and control groups (i.e., Hedges' g) were calculated to quantify the extent of cognitive dysfunction in those groups consisting of children

SUBMITTER: He J 

PROVIDER: S-EPMC6215942 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature