Lactation and progression to type 2 diabetes in patients with gestational diabetes mellitus: A systematic review and meta-analysis of cohort studies.

ABSTRACT:

Aims/introduction

To explore the association between lactation and type 2 diabetes incidence in women with prior gestational diabetes.

Materials and methods

We searched PubMed, Embase and the Cochrane Library for cohort studies published through 12 June 2017 that evaluated the effect of lactation on the development of type 2 diabetes in women with prior gestational diabetes. A random effects model was used to estimate relative risks (RRs) with 95% confidence intervals (CIs).

Results

A total of 13 cohort studies were included in the meta-analysis. The pooled result suggested that compared with no lactation, lactation was significantly associated with a lower risk of type 2 diabetes (RR 0.66, 95% CI 0.48-0.90, I²  = 72.8%, P < 0.001). This relationship was pr

SUBMITTER: Feng L 

PROVIDER: S-EPMC6215952 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature