Support for the Dominance Theory in Drosophila Transcriptomes.

ABSTRACT: Interactions among divergent elements of transcriptional networks from different species can lead to misexpression in hybrids through regulatory incompatibilities, some with the potential to generate sterility. While the possible contribution of faster-male evolution to this misexpression has been explored, the role of the hemizygous X chromosome (i.e., the dominance theory for transcriptomes) remains yet to be determined. Here, we study genome-wide patterns of gene expression in females and males of Drosophila yakuba, Drosophila santomea and their hybrids. We used attached-X stocks to specifically test the dominance theory, and we uncovered a significant contribution of recessive alleles on the X chromosome to hybrid misexpression. Our analyses also sugg

SUBMITTER: Llopart A 

PROVIDER: S-EPMC6216581 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature