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A pendant peptide endows a sunscreen with water-resistance.


ABSTRACT: Ultraviolet light causes skin cancer. Salicylic acid and other molecular filters absorb damaging radiation but are washed away readily. Conjugation to a collagen mimetic peptide is shown to retain salicylic acid on collagen-containing skin surrogates after repeated washing. This strategy, which is highly modular, could enhance the water-resistance of sunscreens.

SUBMITTER: Ellison AJ 

PROVIDER: S-EPMC6217811 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature

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A pendant peptide endows a sunscreen with water-resistance.

Ellison Aubrey J AJ   Raines Ronald T RT  

Organic & biomolecular chemistry 20181001 39


Ultraviolet light causes skin cancer. Salicylic acid and other molecular filters absorb damaging radiation but are washed away readily. Conjugation to a collagen mimetic peptide is shown to retain salicylic acid on collagen-containing skin surrogates after repeated washing. This strategy, which is highly modular, could enhance the water-resistance of sunscreens. ...[more]

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