Highlighting the Potency of Biosurfactants Produced by Pseudomonas Strains as Anti-Legionella Agents.

ABSTRACT: Legionella pneumophila, the causative agent of Legionnaires' disease, is a waterborne bacterium mainly found in man-made water systems in close association with free-living amoebae and multispecies biofilms. Pseudomonas strains, originating from various environments including freshwater systems or isolated from hospitalized patients, were tested for their antagonistic activity towards L. pneumophila. A high amount of tested strains was thus found to be active. This antibacterial activity was correlated to the presence of tensioactive agents in culture supernatants. As Pseudomonas strains were known to produce biosurfactants, these compounds were specifically extracted and purified from active strains and further characterized using reverse-phase HPLC and mass sp

SUBMITTER: Loiseau C 

PROVIDER: S-EPMC6217892 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature