Antenatal placental assessment in the prediction of adverse pregnancy outcome after reduced fetal movement.

ABSTRACT:

Objective

To assess the value of in utero placental assessment in predicting adverse pregnancy outcome after reported reduced fetal movements (RFM).

Method

A non-interventional prospective cohort study of women (N = 300) with subjective RFM at ≥28 weeks' gestation in singleton non-anomalous pregnancies at a UK tertiary maternity hospital. Clinical, sonographic (fetal weight, placental size and maternal, fetal and placental arterial Doppler) and biochemical (maternal serum hCG, hPL, progesterone, PlGF and sFlt-1) assessment was conducted. Multiple logistic regression identified combinations of measurements (models) most predictive of adverse pregnancy outcome (perinatal mortality, birth weight <10th centile, five minute Apgar score <7, umbilical arterial pH <7.1 or base exces

SUBMITTER: Higgins LE 

PROVIDER: S-EPMC6218043 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature