Towards non-invasive characterisation of coronary stent re-endothelialisation - An in-vitro, electrical impedance study.

ABSTRACT: The permanent implantation of a stent has become the most common method for ameliorating coronary artery narrowing arising from atherosclerosis. Following the procedure, optimal arterial wall healing is characterised by the complete regrowth of an Endothelial Cell monolayer over the exposed stent surface and surrounding tissue, thereby reducing the risk of thrombosis. However, excessive proliferation of Smooth Muscle Cells, within the artery wall can lead to unwanted renarrowing of the vessel lumen. Current imaging techniques are unable to adequately identify re-endothelialisation, and it has previously been reported that the stent itself could be used as an electrode in combination with electrical impedance spectroscopic techniques to monitor the post-stenting recovery phase. The utility

SUBMITTER: Holland I 

PROVIDER: S-EPMC6218196 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature