Association between early life antibiotic use and childhood overweight and obesity: a narrative review.

ABSTRACT:

Background

Recent research implicates antibiotic use as a potential contributor to child obesity risk. In this narrative review, we examine current observational evidence on the relation between antibiotic use in early childhood and subsequent measures of child body mass.

Methods

We searched PubMed, Web of Science and the Cochrane Library to identify studies that assessed antibiotic exposure before 3 years of age and subsequent measures of body mass or risk of overweight or obesity in childhood.

Results

We identified 13 studies published before October 2017, based on a total of 6 81 332 individuals, which examined the relation between early life antibiotic exposure and measures of child body mass. Most studies did not appropriately account for confounding by indicatio

SUBMITTER: Partap U 

PROVIDER: S-EPMC6218928 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature