Three-Dimensional Mitral Valve Morphology in Children and Young Adults With Marfan Syndrome.

ABSTRACT:

Background

Mitral valve (MV) prolapse is common in children with Marfan syndrome (MFS) and is associated with varying degrees of mitral regurgitation (MR). However, the three-dimensional (3D) morphology of the MV in children with MFS and its relation to the degree of MR are not known. The goals of this study were to describe the 3D morphology of the MV in children with MFS and to compare it to that in normal children.

Methods

Three-dimensional transthoracic echocardiography was performed in 27 patients (3-21 years of age) meeting the revised Ghent criteria for MFS and 27 normal children matched by age (±1 year). The 3D geometry of the MV apparatus in midsystole was measured, and its association with clinical and two-dimensional echocardiographic parameters was examined.

R

SUBMITTER: Jolley MA 

PROVIDER: S-EPMC6218932 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature