Higher levels of tumor necrosis factor β are associated with frailty in socially vulnerable community-dwelling older adults.

ABSTRACT:

Background

The complex physiology underpinning the frailty syndrome is responsible for the absence of robust biomarkers that can be used for screening, diagnostic and/or prognostic purposes and has made clinical implementation difficult. Considering socially vulnerable populations, who have poor health status and increased morbidity and mortality, this scenario is even more complex. However, to the best of our knowledge, there are no studies available to investigate frailty biomarkers in socially vulnerable populations. Thus, the aim of this cross-sectional study was to identify potential blood-based biomarkers of frailty in a socially vulnerable population.

Methods

A sample consisting of 347 community-dwelling older people living in a context of high social vulnerability wa

SUBMITTER: Nascimento CMC 

PROVIDER: S-EPMC6219095 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature