Whole Genome Sequencing of Mycobacterium bovis Isolated From Livestock in the United States, 1989-2018.

ABSTRACT: The United States official bovine tuberculosis (bTB) eradication program has utilized genotyping for Mycobacterium bovis isolates since 2000 and whole genome sequencing was implemented in 2013. The program has been highly successful, yet as bTB prevalence has reached historic lows, a small number of new bTB-affected cattle herds occur annually. Therefore, understanding the epidemiology of bTB transmission is critically important, in order to target limited resources for surveillance and achieve eradication. This evaluation described the diversity and epidemiology of M. bovis isolates identified in the USA livestock. Isolates from animals within the bTB endemic area of Michigan were excluded. Broad diversity was found among 1,248 isolates, collected from affected cattle and fa

SUBMITTER: Orloski K 

PROVIDER: S-EPMC6219248 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature