White blood cell count and all-cause and cause-specific mortality in the Guangzhou biobank cohort study.

ABSTRACT:

Background

Several studies have shown positive associations between higher WBC count and deaths from all-causes, CHD, stroke and cancer among occidental populations or developed countries of Asia. No study on the association of WBC count with all-cause and cause-specific mortality in Chinese populations was reported. We studied this using prospective data from a large Chinese cohort.

Methods

We used prospective data from the Guangzhou Biobank Cohort Study (GBCS), a total of 29,925 participants in present study. A Cox proportional hazards regression model was used to estimate the hazard ratios (HR) and 95% confidence interval (CI).

Results

The hazard ratios (HR) for all-cause, CHD, and respiratory disease mortality for the highest decile of WBC count (women > 8.2 × 10<

SUBMITTER: Wang T 

PROVIDER: S-EPMC6219250 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature