High intensity resistance training causes muscle damage and increases biomarkers of acute kidney injury in healthy individuals.

ABSTRACT:

Purpose

High-intensity interval resistance training (HIIRT) is an increasingly popular exercise program that provides positive results with short sessions. This study aimed to evaluate whether an HIIRT session causes muscle and kidney damage.

Methods

Fifty-eight healthy volunteers (median age 24 years, 50% women) participated in this study and performed a HIIRT session. The Borg CR10 scale for pain (CR10P) and blood and urine samples were collected before (baseline) and 2 and 24 hours after the HIIRT session. Blood samples were analyzed for serum creatinine (SCr), creatine kinase (CK) and myoglobin. Urine samples were assessed for creatinine, neutrophil gelatinase-associated lipocalin, interleukin 18, calbindin, microalbuminuria, trefoil factor-3 and β-2 microglobulin.

Re

SUBMITTER: Spada TC 

PROVIDER: S-EPMC6219767 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature