Longitudinal analysis of developmental changes in electroencephalography patterns and sleep-wake states of the neonatal mouse.

ABSTRACT: The neonatal brain undergoes rapid maturational changes that facilitate the normal development of the nervous system and also affect the pathological response to brain injury. Electroencephalography (EEG) and analysis of sleep-wake vigilance states provide important insights into the function of the normal and diseased immature brain. While developmental changes in EEG and vigilance states are well-described in people, less is known about the normal maturational properties of rodent EEG, including the emergence and evolution of sleep-awake vigilance states. In particular, a number of developmental EEG studies have been performed in rats, but there is limited comparable research in neonatal mice, especially as it pertains to longitudinal EEG studies performed within the same mouse. In this

SUBMITTER: Rensing N 

PROVIDER: S-EPMC6219806 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature