Emphysema quantification using chest CT: influence of radiation dose reduction and reconstruction technique.

ABSTRACT:

Background

Computed tomography (CT) emphysema quantification is affected by both radiation dose (i.e. image noise) and reconstruction technique. At reduced dose, filtered back projection (FBP) results in an overestimation of the amount of emphysema due to higher noise levels, while the use of iterative reconstruction (IR) can result in an underestimation due to reduced noise. The objective of this study was to determine the influence of dose reduction and hybrid IR (HIR) or model-based IR (MIR) on CT emphysema quantification.

Methods

Twenty-two patients underwent inspiratory chest CT scan at routine radiation dose and at 45%, 60% and 75% reduced radiation dose. Acquisitions were reconstructed with FBP, HIR and MIR. Emphysema was quantified using the 15th percentile of the at

SUBMITTER: den Harder AM 

PROVIDER: S-EPMC6220000 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature