Microbiome shifts with onset and progression of Sea Star Wasting Disease revealed through time course sampling.

ABSTRACT: The recent outbreak of Sea Star Wasting Disease (SSWD) is one of the largest marine epizootics in history, but the host-associated microbial community changes specific to disease progression have not been characterized. Here, we sampled the microbiomes of ochre sea stars, Pisaster ochraceus, through time as animals stayed healthy or became sick and died with SSWD. We found community-wide differences in the microbiomes of sick and healthy sea stars, changes in microbial community composition through disease progression, and a decrease in species richness of the microbiome in late stages of SSWD. Known beneficial taxa (Pseudoalteromonas spp.) decreased in abundance at symptom onset and through disease progression, while known pathogenic (Tenacibaculum spp.) and putatively opportunistic bacte

SUBMITTER: Lloyd MM 

PROVIDER: S-EPMC6220307 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature