Preconception Plasma Phospholipid Fatty Acids and Fecundability.

ABSTRACT:

Context

Fatty acids (FAs) are important for reproductive processes, including steroidogenesis, though associations with fecundability, as measured by time to pregnancy (TTP), are unclear.

Objective

To investigate the relationship between preconception plasma phospholipid FA (PPFA) levels and time to human chorionic gonadotropin-pregnancy among women with prior pregnancy loss.

Design, setting, and participants

Prospective cohort of 1228 women attempting pregnancy (aged 18 to 40 years, with one or two prior pregnancy losses) followed for up to six cycles at four US university medical centers during 2006 to 2012. PPFA levels were measured at baseline.

Main outcome measures

Associations with fecundability overall and by body mass index (BMI) group after adjusting f

SUBMITTER: Mumford SL 

PROVIDER: S-EPMC6220440 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature