Development and Validation of Objective and Quantitative Eye Tracking-Based Measures of Autism Risk and Symptom Levels.

ABSTRACT:

Objective

The primary aim of this study was to develop and validate eye tracking-based measures for estimating autism spectrum disorder (ASD) risk and quantifying autism symptom levels.

Method

Eye tracking data were collected from youth during an initial evaluation visit, with administrators blinded to all clinical information. Consensus diagnoses were given by the multidisciplinary team. Participants viewed a 5-minute video that included 44 dynamic stimuli from 7 distinct paradigms while gaze was recorded. Gaze metrics were computed for temporally defined regions of interest. Autism risk and symptom indices aggregated gaze measures showing significant bivariate relationships with ASD diagnosis and Autism Diagnostic Observation Schedule, Second Edition (ADOS-2) symptom sever

SUBMITTER: Frazier TW 

PROVIDER: S-EPMC6220711 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature