Timing of Exposure and Bisphenol-A: Implications for Diabetes Development.

ABSTRACT: Bisphenol-A (BPA) is one of the most widespread endocrine disrupting chemicals (EDCs). It is used as the base compound in the production of polycarbonate and other plastics present in many consumer products. It is also used as a building block in epoxy can coating and the thermal paper of cash register receipts. Humans are consistently exposed to BPA and, in consequence, this compound has been detected in the majority of individuals examined. Over the last decade, an enlarging body of evidence has provided a strong support for the role of BPA in the etiology of diabetes and other metabolic disorders. Timing of exposure to EDCs results crucial since it has important implications on the resulting adverse effects. It is now well established that the developing organisms are particularly sensi

SUBMITTER: Tuduri E 

PROVIDER: S-EPMC6220716 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature