Dataset Information
Mechanochemical Activation of Zinc and Application to Negishi Cross-Coupling.
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ABSTRACT:
SUBMITTER: Cao Q
PROVIDER: S-EPMC6220771 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Publications
Mechanochemical Activation of Zinc and Application to Negishi Cross-Coupling.
Angewandte Chemie (International ed. in English) 20180802 35
A form independent activation of zinc, concomitant generation of organozinc species and engagement in a Negishi cross-coupling reaction via mechanochemical methods is reported. The reported method exhibits a broad substrate scope for both C(sp<sup>3</sup> )-C(sp<sup>2</sup> ) and C(sp<sup>2</sup> )-C(sp<sup>2</sup> ) couplings and is tolerant to many important functional groups. The method may offer broad reaching opportunities for the in situ generation organometallic compounds from base metals ...[more]