Quality of life in coeliac disease: item reduction, scale development and psychometric evaluation of the Coeliac Disease Assessment Questionnaire (CDAQ).

ABSTRACT:

Background

A better understanding of coeliac disease can be achieved by assessing health-related quality of life alongside clinical factors. Existing patient-reported outcome measures (PROMs) evaluating quality of life in coeliac disease have not been developed in accordance with the US Food and Drug Administration guidelines.

Aim

To develop a PROM in accordance with best practice guidelines, capturing all aspects of quality of life important to adults with coeliac disease.

Methods

Candidate items for the Coeliac Disease Assessment Questionnaire (CDAQ) were refined through item appraisal, expert review, cognitive interviews, and a translatability assessment. A cross-sectional survey determined further item reduction and the CDAQ's structure. The final CDAQ was adminis

SUBMITTER: Crocker H 

PROVIDER: S-EPMC6220785 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature