Resting-state basal ganglia network codes a motor musical skill and its disruption From dystonia.

ABSTRACT:

Background

Musician's dystonia critically impacts professional musicians' careers as they may lose musical skills, which have been acquired through long and intensive training. Yet the pathophysiology of musician's dystonia and its link to the neural mechanisms supporting musical skills is poorly understood. We tested if resting-state functional connectivity might reflect an aspect of musical skill linked to the pathophysiology of musician's dystonia. We also tested a second hypothesis that the region with altered resting-state functional connectivity might be correlated with a quantitative measure of musical skills.

Methods

We studied 21 patients with musician's dystonia affecting their hands and 34 healthy musicians, using resting-state functional magnetic resonance imagin

SUBMITTER: Kita K 

PROVIDER: S-EPMC6220822 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature