Ontology highlight
ABSTRACT:
SUBMITTER: Tamura R
PROVIDER: S-EPMC6221051 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Genes, chromosomes & cancer 20181101 11
Primary ovarian sarcomas are extremely rare tumors, and their genomic and transcriptomic alterations remain to be elucidated. We performed whole exome sequencing of primary tumor and matched normal blood samples derived from one patient with ovarian undifferentiated small round cell sarcoma. We identified 8 nonsynonymous somatic mutations, and all mutations were missense or nonsense changes. Next, we performed RNA sequencing of the tumor sample and identified two in-frame fusion transcripts: MXD ...[more]